Christine L. Hann

Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

Daniel D. Von Hoff, Patricia LoRusso, Charles M. Rudin et al. · New England Journal of Medicine · 2009 · 1.1K citations · Full text

Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

Charles M. Rudin, Christine L. Hann, John Laterra et al. · New England Journal of Medicine · 2009 · 1K citations · Full text

Neuro-oncology, Tumoral Pathology, Hedgehog Signaling +12

<i>Smoothened</i> Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

Robert L. Yauch, Gerrit J.P. Dijkgraaf, Bruno Alicke et al. · Science · 2009 · 837 citations · Full text

Health Sciences, Glioma, Genetics +14

Phase I Study of Navitoclax (ABT-263), a Novel Bcl-2 Family Inhibitor, in Patients With Small-Cell Lung Cancer and Other Solid Tumors

Leena Gandhi, D. Ross Camidge, Moacyr Oliveira et al. · Journal of Clinical Oncology · 2011 · 579 citations · Full text

Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors

Patricia LoRusso, Charles M. Rudin, Josina C. Reddy et al. · Clinical Cancer Research · 2011 · 544 citations · Full text