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Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform

Medicinal ChemistryPharmaceutical ScienceBiochemistryNatural SciencesMedicineSelective InhibitorsAnti-cancer AgentDrug DevelopmentChemical BiologyPharmacologyPharmaceutical ChemistryDual-tail Arylsulfone-based BenzenesulfonamidesDrug DiscoveryHydrophilic Halves