Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII

Hany S. Ibrahim, Sahar M. Abou‐Seri, Muhammet Tanç, +3

European Journal of Medicinal Chemistry

Medicinal ChemistryMedicineIsatin-pyrazole Benzenesulfonamide HybridsAnti-cancer AgentDrug Development +5

3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights

Mahmoud F. Abo-Ashour, Wagdy M. Eldehna, Alessio Nocentini, +9

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryMedicineSilico InsightsNatural Sciences +9

Improvement of antibacterial activity of some sulfa drugs through linkage to certain phthalazin-1(2H)-one scaffolds

Hany S. Ibrahim, Wagdy M. Eldehna, Hatem A. Abdel‐Aziz, +2

European Journal of Medicinal Chemistry

-One ScaffoldsMedicineAntibacterial ActivityAntibiotic AdjuvantAntibacterial Agent +7

Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and<i>in vitro</i>biological evaluation

Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Hany S. Ibrahim, +5

Journal of Enzyme Inhibition and Medicinal Chemistry

Pyridine-Ureas as Potential Anticancer Agents: Synthesis and In Vitro Biological Evaluation

Mohamed El‐Naggar, Hadia Almahli, Hany S. Ibrahim, +2

Molecules

One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells

Wagdy M. Eldehna, Dina H. Elnaggar, Ahmed R. Hamed, +3

Journal of Enzyme Inhibition and Medicinal Chemistry

Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform

Hany S. Ibrahim, Heba Abdelrasheed Allam, Walaa R. Mahmoud, +6

European Journal of Medicinal Chemistry

Medicinal ChemistryPharmaceutical ScienceBiochemistryNatural SciencesMedicine +9

Design, synthesis and in vitro antitumor activity of novel N-substituted-4-phenyl/benzylphthalazin-1-ones

Wagdy M. Eldehna, Hany S. Ibrahim, Hatem A. Abdel‐Aziz, +2

European Journal of Medicinal Chemistry

Medicinal ChemistryDerivative (Chemistry)EngineeringMedicineDrug Discovery +7

Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies

Mahmoud F. Abo-Ashour, Wagdy M. Eldehna, Alessio Nocentini, +4

European Journal of Medicinal Chemistry

EngineeringMedicineOrganic ChemistryMolecular Modeling StudiesSynthetic Chemistry +6

Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking

Wagdy M. Eldehna, Mohamed Farès, Hany S. Ibrahim, +6

European Journal of Medicinal Chemistry

Molecular DockingMedicinal ChemistryDrug TargetingChemoprevention StrategyMedicine +9