Alessio Nocentini

Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies

Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2017 · 143 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +9

Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations

Alessio Nocentini, Marta Ferraroni, Fabrizio Carta et al. · Journal of Medicinal Chemistry · 2016 · 108 citations · Full text

3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights

Mahmoud F. Abo-Ashour, Wagdy M. Eldehna, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2019 · 106 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11

Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action

Alessandro Bonardi, Alessio Nocentini, Silvia Bua et al. · Journal of Medicinal Chemistry · 2020 · 106 citations · Full text

Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents

Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2018 · 98 citations · Full text

Tail Hydrophobic Interactions, Combinatorial Chemistry, Medicinal Chemistry +11