Alessandro Bonardi

3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights

Mahmoud F. Abo-Ashour, Wagdy M. Eldehna, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2019 · 106 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11

Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action

Alessandro Bonardi, Alessio Nocentini, Silvia Bua et al. · Journal of Medicinal Chemistry · 2020 · 106 citations · Full text

Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents

Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2018 · 98 citations · Full text

Tail Hydrophobic Interactions, Combinatorial Chemistry, Medicinal Chemistry +11

Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms

Alessio Nocentini, Alessandro Bonardi, Paola Gratteri et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2018 · 79 citations · Full text

3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies

Abdulsalam A. M. Alkhaldi, Mohammad M. Al‐Sanea, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2020 · 76 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +10