Mahmoud F. Abo-Ashour

Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies

Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2017 · 143 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +9

3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights

Mahmoud F. Abo-Ashour, Wagdy M. Eldehna, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2019 · 106 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11

Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents

Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2018 · 98 citations · Full text

Tail Hydrophobic Interactions, Combinatorial Chemistry, Medicinal Chemistry +11

Novel indole-thiazolidinone conjugates: Design, synthesis and whole-cell phenotypic evaluation as a novel class of antimicrobial agents

Mahmoud F. Abo-Ashour, Wagdy M. Eldehna, Riham F. George et al. · European Journal of Medicinal Chemistry · 2018 · 97 citations

Antifungal Agent, Novel Indole-thiazolidinone Conjugates, Medicine +10

Development of isatin-thiazolo[3,2-a]benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and molecular dynamics investigations

Wagdy M. Eldehna, Mahmoud A. El Hassab, Mahmoud F. Abo-Ashour et al. · Bioorganic Chemistry · 2021 · 97 citations

Medicinal Chemistry, Medicine, Molecular Dynamics Investigations +10