Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents

Publication | Open Access

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References

2018

Year

Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini, Radwan El‐Haggar, Silvia Bua, Alessandro Bonardi, Sara T. Al‐Rashood, Ghada S. Hassan, Paola Gratteri, Hatem A. Abdel‐Aziz,

European Journal of Medicinal Chemistry

Tail Hydrophobic InteractionsCombinatorial ChemistryMedicinal ChemistryPharmaceutical ChemistryBioorganic ChemistryBiochemistryNatural SciencesMedicineBioconjugationChemical BiologyPharmacologyStructural ExtensionDrug DiscoveryCarbonic Anhydrase Inhibitors