Silvia Bua

Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs–CAIs) for the Treatment of Rheumatoid Arthritis

Silvia Bua, Lorenzo Di Cesare Mannelli, Daniela Vullo et al. · Journal of Medicinal Chemistry · 2017 · 131 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action

Alessandro Bonardi, Alessio Nocentini, Silvia Bua et al. · Journal of Medicinal Chemistry · 2020 · 113 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights

Mahmoud F. Abo-Ashour, Wagdy M. Eldehna, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2019 · 108 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents

Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini et al. · European Journal of Medicinal Chemistry · 2018 · 99 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases

Alessio Nocentini, Silvia Bua, Carrie L. Lomelino et al. · ACS Medicinal Chemistry Letters · 2017 · 76 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14