Carrie L. Lomelino

Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action

Alessandro Bonardi, Alessio Nocentini, Silvia Bua et al. · Journal of Medicinal Chemistry · 2020 · 113 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases

Alessio Nocentini, Silvia Bua, Carrie L. Lomelino et al. · ACS Medicinal Chemistry Letters · 2017 · 76 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111

Carrie L. Lomelino, Brian P. Mahon, Robert McKenna et al. · Bioorganic & Medicinal Chemistry · 2016 · 70 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Inclusion of a 5-fluorouracil moiety in nitrogenous bases derivatives as human carbonic anhydrase IX and XII inhibitors produced a targeted action against MDA-MB-231 and T47D breast cancer cells

Andrea Petreni, Alessandro Bonardi, Carrie L. Lomelino et al. · European Journal of Medicinal Chemistry · 2020 · 70 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of β-Adrenergic Receptors Blocker–Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy

Alessio Nocentini, Mariangela Ceruso, Silvia Bua et al. · Journal of Medicinal Chemistry · 2018 · 64 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14