Dietary Slowly Digestible Starch Triggers the Gut–Brain Axis in Obese Rats with Accompanied Reduced Food Intake

Abstract

SDS with digestion into the ileum reduced daily food intake and paralleled suppressed expression of appetite-stimulating neuropeptide genes associated with the gut-brain axis. This novel finding suggests further exploration involving a clinical study and potential development of SDS-based functional foods as an approach to obesity control.