Concepedia

miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma

Yuqiong Wang, Xiyu Zhang, Wei Tang, Zhenghong Lin, Limei Xu, Ruifen Dong, Yinuo Li, Jieyin Li, Zaixin Zhang, Xiangzhi Li,

Cell Death and Differentiation · 2017 · 71 citations · 27 references

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27

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3.1K citations

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Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb

Andrew R. Tee, Brendan D. Manning, Philippe P. Roux et al. · Current Biology · 2003 · 1.2K citations · Full text

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IKKβ Suppression of TSC1 Links Inflammation and Tumor Angiogenesis via the mTOR Pathway

Dung‐Fang Lee, Hsu-Ping Kuo, Chun‐Te Chen et al. · Cell · 2007 · 630 citations · Full text

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Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells

Hua Zhu, Hao Wu, Xiuping Liu et al. · Autophagy · 2009 · 441 citations · Full text

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A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1

Osman Nidai Özeş, Hakan Akça, Lindsey D. Mayo et al. · Proceedings of the National Academy of Sciences · 2001 · 380 citations · Full text

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