IKKβ Suppression of TSC1 Links Inflammation and Tumor Angiogenesis via the mTOR Pathway

IKKε and TBK1 are essential components of the IRF3 signaling pathway

Katherine A. Fitzgerald, Sarah M. McWhirter, Daniel C. Rowe et al. · Nature Immunology · 2003 · 2.7K citations

Life Sciences, Biochemistry, Molecular Biology +6

IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Florian R. Greten, Lars Eckmann, Tim F. Greten et al. · Cell · 2004 · 2.4K citations · Full text

Medicine, Immunology, Oncology +16

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Ken Inoki, Yong Li, Tian Xu et al. · Genes & Development · 2003 · 1.9K citations · Full text

Life Sciences, Cell Biology, Genetics +15

TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Ken Inoki, Hongjiao Ouyang, Tianqing Zhu et al. · Cell · 2006 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +17

Phosphorylation and Functional Inactivation of TSC2 by Erk

Li Ma, Zhenbang Chen, Hediye Erdjument‐Bromage et al. · Cell · 2005 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8