Concepedia

Phosphorylation and Functional Inactivation of TSC2 by Erk

Li Ma, Zhenbang Chen, Hediye Erdjument‐Bromage, Paul Tempst, Pier Paolo Pandolfi

Cell · 2005 · 1.3K citations · 53 references

DOIFull text

Open access

Concepts

References

53

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.9K citations · Full text

, , +10

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3.1K citations

, , +6

Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms

Azad Bonni, Anne Brunet, Anne E. West et al. · Science · 1999 · 1.9K citations

, , +17

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Ken Inoki, Yong Li, Tian Xu et al. · Genes & Development · 2003 · 1.9K citations · Full text

, , +15

Identification of the Tuberous Sclerosis Gene <i>TSC1</i> on Chromosome 9q34

Marjon van Slegtenhorst, Ronald De Hoogt, Caroline Hermans et al. · Science · 1997 · 1.7K citations

, , +16