Philippe P. Roux

Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb

Andrew R. Tee, Brendan D. Manning, Philippe P. Roux et al. · Current Biology · 2003 · 1.2K citations · Full text

Protein Function, Signal Transduction, Gtpase-activating Protein Complex +7

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

Andrew Y. Choo, Sang-Oh Yoon, Sang Gyun Kim et al. · Proceedings of the National Academy of Sciences · 2008 · 781 citations · Full text

Molecular Regulation, Mrna Translation, Molecular Biology +18

RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation

Philippe P. Roux, David Shahbazian, Hieu Vu et al. · Journal of Biological Chemistry · 2007 · 741 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +9

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

Philippe P. Roux, Bryan A. Ballif, Rana Anjum et al. · Proceedings of the National Academy of Sciences · 2004 · 740 citations · Full text

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

David Shahbazian, Philippe P. Roux, Virginie Mieulet et al. · The EMBO Journal · 2006 · 525 citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +9