Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

Andrew Y. Choo, Sang-Oh Yoon, Sang Gyun Kim, +2

Proceedings of the National Academy of Sciences

Molecular RegulationMrna TranslationMolecular BiologyMtorc1 ComplexCellular Physiology +16

The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4

Alfred Csibi, Sarah‐Maria Fendt, Chenggang Li, +13

Cell

Signal TransductionCell RegulationMolecular PathwayMolecular RegulationCell Proliferation +5

Glucose Addiction of TSC Null Cells Is Caused by Failed mTORC1-Dependent Balancing of Metabolic Demand with Supply

Andrew Y. Choo, Sang Gyun Kim, Matthew G. Vander Heiden, +5

Molecular Cell

Metabolic SyndromeEnergy HomeostasisMedicineGlucose AddictionPhysiology +9

Metabolic Stress Controls mTORC1 Lysosomal Localization and Dimerization by Regulating the TTT-RUVBL1/2 Complex

Sang Gyun Kim, Gregory R. Hoffman, George Poulogiannis, +8

Molecular Cell

Signal TransductionMolecular RegulationMedicineNatural SciencesMolecular Biology +5

Coimmunization with an Optimized IL-15 Plasmid Results in Enhanced Function and Longevity of CD8 T Cells That Are Partially Independent of CD4 T Cell Help

Michele A. Kutzler, Tara M. Robinson, Michael A. Chattergoon, +15

The Journal of Immunology

Induction of Inflammation by<i>West Nile virus</i>Capsid through the Caspase-9 Apoptotic Pathway

Joo-Sung Yang, Mathura P. Ramanathan, Kar Muthumani, +10

Emerging infectious diseases

The organization of adherens junctions and desmosomes at the cardiac intercalated disc is independent of gap junctions

David E. Gutstein, Fangyu Liu, Marian B. Meyers, +2

Journal of Cell Science

Induction of Potent Th1‐Type Immune Responses from a Novel DNA Vaccine for West Nile Virus New York Isolate (WNV‐NY1999)

Joo‐Sung Yang, J. Joseph Kim, Daniel S. Hwang, +6

The Journal of Infectious Diseases

Human Immunodeficiency Virus Type 1 Nef Induces Programmed Death 1 Expression through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism

Kar Muthumani, Andrew Y. Choo, Devon J. Shedlock, +10

Journal of Virology

ApoptosisImmunologyCell DeathImmunologic MechanismCd4 T Cell Responses +16

The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1

Kar Muthumani, Andrew Y. Choo, Wei‐Xing Zong, +8

Nature Cell Biology

Viral ReplicationSignal TransductionGlucocorticoid Receptor ComplexG Protein-coupled ReceptorHuman Retrovirus +11