Gregory R. Hoffman - Concepedia

Author

Gregory R. Hoffman

Novartis (Switzerland)

Also Known As

G. R. Hoffman, G.R. Hoffman, Gregory Hoffman, Gregory R Hoffman, Gregory R. Hoffman, Gregory R. Hoffman, Harris, Donna

Publications

6.9K

Citations

H-Index

Concepts

All Affiliations

Novartis (Switzerland)Harvard University Novartis Institutes for BioMedical Research Novartis (United States)Cornell University

About

Gregory R. Hoffman is an author at Novartis (Switzerland) specializing in medicine, cell biology, and cell signaling.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	17	17	4.8K
2	Natural Sciences	6	6	1.2K
3	Engineering	2	2	767
4	Education	1	1	21
5	Health Sciences	1	1	868

Gregory R. Hoffman

Publications

6.6K

Citations

H-Index

Page 1

	Year	Citations
p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells Robert J. Ihry, Kathleen A. Worringer, Max R. Salick, Nature Medicine MedicineStem Cell EngineeringStem CellsStem Cell ResearchGenome Engineering	2018	988
Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling Yonghao Yu, Sang-Oh Yoon, George Poulogiannis, Science Insulin SignalingSignaling PathwayReceptor Tyrosine KinaseRadiation OncologyCell Signaling	2011	868
Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening E. Robert McDonald, Antoine de Weck, Michael R. Schlabach, Cell BioinformaticsTumor BiologyRadiation OncologyFunctional GenomicsProject Drive	2017	687
Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5 Konstantinos J. Mavrakis, E. Robert McDonald, Michael R. Schlabach, Science	2016	538
DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks Megan van Overbeek, Daniel Capurso, Matthew M. Carter, Molecular Cell Genome InstabilityDna DamageDna AnalysisMolecular BiologyCas9-mediated Breaks	2016	494
Structure of the Rho Family GTP-Binding Protein Cdc42 in Complex with the Multifunctional Regulator RhoGDI Gregory R. Hoffman, Nicolas Nassar, Richard A. Cerione Cell Multifunctional Regulator RhogdiSignal TransductionProtein FunctionBiochemistryMolecular Regulation	2000	491
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers Gregory R. Hoffman, Rami Rahal, Frank P. Buxton, Proceedings of the National Academy of Sciences	2014	405
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy Christina H. Eng, Zuncai Wang, Diane Tkach, Proceedings of the National Academy of Sciences Kras Mutant TumorsAutophagy InhibitorsImmunologyPathologyCell Proliferation	2015	221
Metabolic Stress Controls mTORC1 Lysosomal Localization and Dimerization by Regulating the TTT-RUVBL1/2 Complex Sang Gyun Kim, Gregory R. Hoffman, George Poulogiannis, Molecular Cell Signal TransductionMolecular RegulationMedicineNatural SciencesMolecular Biology	2012	211
YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury Lara Planas‐Paz, Tianliang Sun, Monika Pikiolek, Cell stem cell Signal TransductionDevelopmental BiologyHepatologyLiver InjuryBiliary Epithelial Cells	2019	206

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