Antoine de Weck

Next-generation characterization of the Cancer Cell Line Encyclopedia

Mahmoud Ghandi, Franklin W. Huang, Judit Jané‐Valbuena et al. · Nature · 2019 · 3.5K citations · Full text

Tumor Heterogeneity, Medicine, Cancer Genomics +6

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach et al. · Cell · 2017 · 687 citations · Full text

Bioinformatics, Tumor Biology, Radiation Oncology +13

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Konstantinos J. Mavrakis, E. Robert McDonald, Michael R. Schlabach et al. · Science · 2016 · 538 citations

CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions

Diana M. Muñoz, Pamela J. Cassiani, Li Li et al. · Cancer Discovery · 2016 · 373 citations

TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts

Angelo L. Grauel, Beverly Nguyen, David A. Ruddy et al. · Nature Communications · 2020 · 191 citations · Full text