The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

Wei Tang, Yi Lu, Qingyun Tian, +18

Science

ImmunologyRenal InflammationCell DeathImmune RegulationTnfα Signaling +20

Inactivation of Stat5 in Mouse Mammary Epithelium during Pregnancy Reveals Distinct Functions in Cell Proliferation, Survival, and Differentiation

Yongzhi Cui, Gregory Riedlinger, Keiko Miyoshi, +5

Molecular and Cellular Biology

Developmental BiologyTissue DevelopmentGeneticsMouse Mammary EpitheliumSignal Transducers +13

Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism

Yi Fu, Yu Sun, Mei Wang, +17

Cell Metabolism

Metabolic SyndromeRenal FunctionPodocyte Lipid MetabolismMedicinePhysiology +8

PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy

Di Zhou, Meng Zhou, Ziying Wang, +9

Cell Death and Disease

Endothelial SIRT6 Is Vital to Prevent Hypertension and Associated Cardiorenal Injury Through Targeting Nkx3.2-GATA5 Signaling

Jian Guo, Ziying Wang, Jichao Wu, +13

Circulation Research

NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy

Pengchao Du, Baoxia Fan, Huirong Han, +12

Kidney International

InflammationUrologyRenal DiseasePodocyte Insulin ResistanceRenal Function +11

Granulin epithelin precursor: a bone morphogenic protein 2‐inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis

Jian Q. Feng, Fengjin Guo, Baichun Jiang, +5

The FASEB Journal

PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner

Fanhua Wei, Yuying Zhang, Jinlong Jian, +7

Scientific Reports

Progranulin protects against renal ischemia/reperfusion injury in mice

Meng Zhou, Wei Tang, Yi Fu, +13

Kidney International

InflammationRenal FunctionMedicineImmunologyRenal Inflammation +7

Optimal dietary alpha-linolenic acid/linoleic acid ratio improved digestive and absorptive capacities and target of rapamycin gene expression of juvenile grass carp (<i>Ctenopharyngodon idellus</i>)

Yun‐Yun Zeng, Wei‐Dan Jiang, Yuxin Liu, +9

Aquaculture Nutrition

NutritionExperimental NutritionFeed AdditiveCk Mrna AbundancesMolecular Nutrition +20