Knockdown of PRMT1 suppresses IL-1β-induced cartilage degradation and inflammatory responses in human chondrocytes through Gli1-mediated Hedgehog signaling pathway

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Jeffrey Lee, Kenneth A. Platt, Patricia Censullo et al. · Development · 1997 · 639 citations

Life Sciences, Developmental Biology, Genetics +17

Identification of a central role for complement in osteoarthritis

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Life Sciences, Immunology, Orthopaedic Surgery +12

Role of interleukin‐1 and tumor necrosis factor α in matrix degradation of human osteoarthritic cartilage

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Medicine, Immunology, Orthopaedic Surgery +17

Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis

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Medicine, Cell Biology, Molecular Biology +17

Purmorphamine activates the Hedgehog pathway by targeting Smoothened

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Life Sciences, Molecular Biology, Pharmacology +7