Ginette R. Squires

Role of interleukin‐1 and tumor necrosis factor α in matrix degradation of human osteoarthritic cartilage

Masahiko Kobayashi, Ginette R. Squires, Aisha Mousa et al. · Arthritis & Rheumatism · 2005 · 505 citations

Medicine, Immunology, Orthopaedic Surgery +17

Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions.

Elena V. Tchetina, Ginette R. Squires, A. Robin Poole · PubMed · 2005 · 215 citations

Medicine, Orthopaedic Surgery, Pathology +17

The pathobiology of focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis

Ginette R. Squires, Sharon Okouneff, Mirela Ionescu et al. · Arthritis & Rheumatism · 2003 · 186 citations

Medicine, Orthopaedic Surgery, Pathobiology +17

Toll‐like receptor 2 (TLR2) and TLR4 are present inside human dendritic cells, associated with microtubules and the Golgi apparatus but are not detectable on the cell surface: integrity of microtubules is required for interleukin‐12 production in response to internalized bacteria

Heli Uronen‐Hansson, Jennifer Allen, Mohamed Osman et al. · Immunology · 2004 · 116 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Differential matrix degradation and turnover in early cartilage lesions of human knee and ankle joints

Matthias Aurich, Ginette R. Squires, A Reiner et al. · Arthritis & Rheumatism · 2005 · 99 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17