Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

Calum C. Bain, Charlotte L. Scott, Heli Uronen‐Hansson, +6

Mucosal Immunology

Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans

Elin Jaensson Gyllenbäck, Heli Uronen‐Hansson, Oliver Pabst, +8

The Journal of Experimental Medicine

Blood PrecursorsT-regulatory CellImmunologyImmune RegulationImmunologic Mechanism +14

IRF4 Transcription-Factor-Dependent CD103+CD11b+ Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation

Emma K. Persson, Heli Uronen‐Hansson, Monika Semmrich, +8

Immunity

DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues

Lionel Franz Poulin, Yasmin Reyal, Heli Uronen‐Hansson, +8

Blood

CD14hiHLA-DRdim macrophages, with a resemblance to classical blood monocytes, dominate inflamed mucosa in Crohn's disease

Susanne Thiesen, Sabina Janciauskiene, Heli Uronen‐Hansson, +5

Journal of Leukocyte Biology

Macrophage and dendritic cell subsets in IBD: ALDH+ cells are reduced in colon tissue of patients with ulcerative colitis regardless of inflammation

Maria K. Magnusson, Siggeir F. Brynjólfsson, Anders Dige, +8

Mucosal Immunology

InflammationDendritic Cell SubsetsAnti-inflammatoryImmunologyGastroenterology +7

Toll‐like receptor 2 (TLR2) and TLR4 are present inside human dendritic cells, associated with microtubules and the Golgi apparatus but are not detectable on the cell surface: integrity of microtubules is required for interleukin‐12 production in response to internalized bacteria

Heli Uronen‐Hansson, Jennifer Allen, Mohamed Osman, +3

Immunology

Microbial PathogensInnate Immune SystemImmunologyImmune RegulationCytoskeleton +25

Context-Dependent Development of Lymphoid Stroma from Adult CD34+ Adventitial Progenitors

Katarzyna Sitnik, Kerstin Wendland, Holger Weishaupt, +5

Cell Reports

Neisseria meningitidis expressing lgtB lipopolysaccharide targets DC-SIGN and modulates dendritic cell function

Liana Steeghs, Sandra J. van Vliet, Heli Uronen‐Hansson, +9

Cellular Microbiology

Dendritic CellInnate Immune SystemImmunologyAntigen ProcessingInnate Immunity +14

Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses

Monika Semmrich, Maud Plantinga, Marcus Svensson, +6

Mucosal Immunology