IRF4 Transcription-Factor-Dependent CD103+CD11b+ Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation

Emma K. Persson, Heli Uronen‐Hansson, Monika Semmrich, +8

Immunity

Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function

Sarah L. Buchan, Lang Dou, Marcus Remer, +26

Immunity

Tumor ImmunologyCancer ImmunosurveillanceAllergyAutoimmune DiseaseT-regulatory Cell +7

Importance of integrin LFA-1 deactivation for the generation of immune responses

Monika Semmrich, Andrew Smith, Carolin Feterowski, +8

The Journal of Experimental Medicine

Integrin Subunit CD18 Is the T-Lymphocyte Receptor for the Helicobacter pylori Vacuolating Cytotoxin

Xaver Sewald, Bettina Gebert‐Vogl, Iris Barwig, +9

Cell Host & Microbe

Molecular ImmunologyMolecular PhysiologySignal TransductionT-lymphocyte ReceptorIntegrin Subunit Cd18 +6

RhoH is important for positive thymocyte selection and T-cell receptor signaling

Tatjana Dorn, Ursula Kuhn, Gerd Bungartz, +13

Blood

Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses

Monika Semmrich, Maud Plantinga, Marcus Svensson, +6

Mucosal Immunology

Design and Synthesis of Potent and Selective α₄β₇Integrin Antagonists

Jürgen Boer, Dirk Gottschling, Anja Schuster, +3

Journal of Medicinal Chemistry

InflammationMolecular PharmacologyMedicinal ChemistryPharmaceutical ChemistryMedicine +8

Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8⁺ T cell immunity to reject ‘cold’ tumors

Monika Semmrich, Jean‐Baptiste Marchand, Laetitia Fend, +15

Journal for ImmunoTherapy of Cancer

Domain binding and isotype dictate the activity of anti-human OX40 antibodies

Jordana Griffiths, Khiyam Hussain, Hannah Smith, +18

Journal for ImmunoTherapy of Cancer

A bispecific IgG format containing four independent antigen binding sites

Anne Ljungars, Torbjörn Schiött, Ulrika Mattson, +6

Scientific Reports

Immunocytochemical TechniqueConventional IggImmunologyMolecular BiologyImmunodominance +17