Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

Alessandra Moretti, Milena Bellin, Andrea Welling, +11

New England Journal of Medicine

Dantrolene rescues arrhythmogenic RYR2 defect in a patient‐specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

Christian Billy Jung, Alessandra Moretti, Michael Mederos y Schnitzler, +14

EMBO Molecular Medicine

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy

Alessandra Moretti, Lina Marie Fonteyne, Florian Giesert, +40

Nature Medicine

Cardiac Muscle FailureCardiomyopathyMuscle FunctionSkeletal MuscleSomatic Cell Genetics +7

EBF2 Regulates Osteoblast-Dependent Differentiation of Osteoclasts

Matthias Kieslinger, Stephanie Folberth, Gergana Dobreva, +5

Developmental Cell

Bone Morphogenic ProteinOsteoblast-dependent DifferentiationMedicineCell BiologyOsteoporosis

Direct Nkx2-5 Transcriptional Repression of Isl1 Controls Cardiomyocyte Subtype Identity

Tatjana Dorn, Alexander Goedel, Jason T. Lam, +13

Stem Cells

Cardiac MuscleImmunologyCardiac Progenitor CellsTranscriptional RegulationSignaling Pathway +18

RhoH is important for positive thymocyte selection and T-cell receptor signaling

Tatjana Dorn, Ursula Kuhn, Gerd Bungartz, +13

Blood

Interplay of cell–cell contacts and RhoA/ <scp>MRTF</scp> ‐A signaling regulates cardiomyocyte identity

Tatjana Dorn, Jessica Kornherr, Elvira Immacolata Parrotta, +24

The EMBO Journal

Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes

Zhifen Chen, Wenying Xian, Milena Bellin, +13

European Heart Journal

Epicardioid single-cell genomics uncovers principles of human epicardium biology in heart development and disease

Anna B. Meier, Dorota Zawada, Maria Teresa De Angelis, +16

Nature Biotechnology

Progressive stretch enhances growth and maturation of 3D stem-cell-derived myocardium

Kun Lü, Thomas Seidel, Xiaochun Cao-Ehlker, +8

Theranostics