Concepedia

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth

Lifeng Yang, Abhinav Achreja, Tsz-Lun Yeung, Lingegowda S. Mangala, Dahai Jiang, Cecil Han, Joelle Baddour, Juan C. Marini, Joseph Ni, Ryuichi Nakahara,

Cell Metabolism · 2016 · 437 citations · 21 references

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Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

Jaekyoung Son, Costas A. Lyssiotis, Haoqiang Ying et al. · Nature · 2013 · 2K citations · Full text

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Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Cosimo Commisso, Shawn M. Davidson, Rengin G. Soydaner-Azeloglu et al. · Nature · 2013 · 1.7K citations

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Metabolic Heterogeneity in Human Lung Tumors

Christopher T. Hensley, Brandon Faubert, Qing Yuan et al. · Cell · 2016 · 1.1K citations · Full text

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Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

Matt I. Gross, Susan D. Demo, Jennifer B. Dennison et al. · Molecular Cancer Therapeutics · 2014 · 1.1K citations

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