Susan D. Demo

Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

Matt I. Gross, Susan D. Demo, Jennifer B. Dennison et al. · Molecular Cancer Therapeutics · 2014 · 1.1K citations

Medicine, Oncology, Pharmacology +16

Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma

Deborah J. Kuhn, Qing Chen, Peter M. Voorhees et al. · Blood · 2007 · 768 citations · Full text

Medicine, Oncology, Pharmacology +13

Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome

Susan D. Demo, Christopher J. Kirk, Monette Aujay et al. · Cancer Research · 2007 · 675 citations · Full text

Medicine, Oncology, Pharmacology +13

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

Tony Muchamuel, Michael Basler, Monette Aujay et al. · Nature Medicine · 2009 · 595 citations

Life Sciences, Immunology, Pathology +17

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Nathalie Jacque, Anne Marie Ronchetti, Clément Larrue et al. · Blood · 2015 · 384 citations · Full text

Medicine, Oncology, Pharmacology +16