Clément Larrue

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Thomas Farge, Estelle Saland, Fabienne de Toni et al. · Cancer Discovery · 2017 · 916 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Nathalie Jacque, Anne Marie Ronchetti, Clément Larrue et al. · Blood · 2015 · 384 citations · Full text

Medicine, Oncology, Pharmacology +16

APR-246 induces early cell death by ferroptosis in acute myeloid leukemia

Rudy Birsen, Clément Larrue, Justine Decroocq et al. · Haematologica · 2021 · 181 citations · Full text

Medicine, Oncology, Pharmacology +17

Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites

Claudie Bosc, Nicolas Broin, Marjorie Fanjul et al. · Nature Communications · 2020 · 155 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells

Clément Larrue, Estelle Saland, Héléna Boutzen et al. · Blood · 2015 · 127 citations

Life Sciences, Cancer Biology, Molecular Biology +16