Isorhamnetin and hyperoside derived from water dropwort inhibits inflammasome activation

Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

Franz Bauernfeind, Gábor Horváth, Andrea Stutz et al. · The Journal of Immunology · 2009 · 2.8K citations · Full text

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae et al. · Nature Medicine · 2015 · 2.7K citations · Full text

Inflammation, Anti-inflammatory, Autoimmune Disease +14

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease

Yun‐Hee Youm, Kim Nguyen, Ryan W. Grant et al. · Nature Medicine · 2015 · 2K citations · Full text

Inflammation, Medicine, Immunology +6

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

Geun‐Shik Lee, Naeha Subramanian, Andrew I. Kim et al. · Nature · 2012 · 1K citations

Inflammation, Signal Transduction, Molecular Physiology +12

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Teresa Fernandes‐Alnemri, Jiang Wu, Je‐Wook Yu et al. · Cell Death and Differentiation · 2007 · 1K citations · Full text

Inflammation, Anti-inflammatory, Signal Transduction +11