Je‐Wook Yu

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Teresa Fernandes‐Alnemri, Je‐Wook Yu, Pinaki Datta et al. · Nature · 2009 · 1.8K citations · Full text

Signal Transduction, Cell Regulation, Cell Interaction +6

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Teresa Fernandes‐Alnemri, Jiang Wu, Je‐Wook Yu et al. · Cell Death and Differentiation · 2007 · 1K citations · Full text

Inflammation, Anti-inflammatory, Signal Transduction +11

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

Teresa Fernandes‐Alnemri, Je‐Wook Yu, Christine A. Juliana et al. · Nature Immunology · 2010 · 700 citations · Full text

Inflammation, Aim2 Inflammasome, Host Response +8

Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome

Christine A. Juliana, Teresa Fernandes‐Alnemri, Jianghong Wu et al. · Journal of Biological Chemistry · 2010 · 593 citations · Full text

SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease

So Ra Kim, Sang‐Guk Lee, Soo Hyun Kim et al. · Nature Communications · 2020 · 489 citations · Full text

Immunology, Cardiovascular Pharmacology, Renal Inflammation +21