Concepedia

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

Teresa Fernandes‐Alnemri, Je‐Wook Yu, Christine A. Juliana, Leobaldo Solórzano, Seokwon Kang, Jianghong Wu, Pinaki Datta, Margaret E. McCormick, Lan Huang, Erin McDermott,

Nature Immunology · 2010 · 711 citations · 38 references

DOIFull text

Open access

Concepts

References

38

Cryopyrin activates the inflammasome in response to toxins and ATP

Sanjeev Mariathasan, David S. Weiss, Kim Newton et al. · Nature · 2006 · 3K citations

, , +7

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

, , +13

Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

Franz Bauernfeind, Gábor Horváth, Andrea Stutz et al. · The Journal of Immunology · 2009 · 2.9K citations · Full text

, , +17

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis et al. · Nature · 2009 · 2.6K citations · Full text

, , +11

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Annett Halle, Veit Hornung, Gabor C. Petzold et al. · Nature Immunology · 2008 · 2.4K citations · Full text

, , +13