Concepedia

Cryopyrin activates the inflammasome in response to toxins and ATP

Sanjeev Mariathasan, David S. Weiss, Kim Newton, Jacqueline McBride, Karen O’Rourke, Meron Roose-Girma, Wyne P. Lee, Yvette Weinrauch, Denise M. Monack, Vishva M. Dixit

Nature · 2006 · 3K citations · 24 references

DOI

Concepts

References

24

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Alexander Poltorak, Xiaolong He, Irina Smirnova et al. · Science · 1998 · 7.6K citations

, , +17

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection

Stephen E. Girardin, Ivo G. Boneca, Jérôme Viala et al. · Journal of Biological Chemistry · 2003 · 2.4K citations · Full text

, , +17

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Sanjeev Mariathasan, Kim Newton, Denise M. Monack et al. · Nature · 2004 · 1.8K citations

, , +14

Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract

Koichi S. Kobayashi, Mathias Chamaillard, Yasunori Ogura et al. · Science · 2005 · 1.8K citations

, , +17