Concepedia

Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex

Tian‐Min Fu, Yang Li, Alvin Lu, Zongli Li, Parimala R. Vajjhala, Anthony Cruz, Devendra B. Srivastava, Frank DiMaio, Pawel A. Penczek, Richard M. Siegel,

Molecular Cell · 2016 · 194 citations · 39 references

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39

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

Marco Biasini, Stefan Bienert, Andrew Waterhouse et al. · Nucleic Acids Research · 2014 · 4.7K citations · Full text

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Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes

Olivier Micheau, Jürg Tschopp · Cell · 2003 · 2.7K citations · Full text

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis et al. · Nature · 2009 · 2.6K citations · Full text

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Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.

Frank Kischkel, Stefan Hellbardt, Iris Behrmann et al. · The EMBO Journal · 1995 · 2.1K citations · Full text

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Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

Alvin Lu, Venkat Giri Magupalli, Jianbin Ruan et al. · Cell · 2014 · 1.3K citations

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