Anthony Cruz

The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

Liwei Wang, Jin Kuk Yang, Venkataraman Kabaleeswaran et al. · Nature Structural & Molecular Biology · 2010 · 267 citations · Full text

Disease Mechanism, Apoptosis, Molecular Biology +10

Memory T cell–driven differentiation of naive cells impairs adoptive immunotherapy

Christopher A. Klebanoff, Christopher D. Scott, Anthony Leonardi et al. · Journal of Clinical Investigation · 2015 · 244 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +19

Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome

Anna Simon, Heiyoung Park, Ravikanth Maddipati et al. · Proceedings of the National Academy of Sciences · 2010 · 199 citations · Full text

Immunology, Immune Regulation, Pathology +20

Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor

Qingshan Fu, Tian‐Min Fu, Anthony Cruz et al. · Molecular Cell · 2016 · 179 citations · Full text

Signal Transduction, G Protein-coupled Receptor, Natural Sciences +15

Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex

Tian‐Min Fu, Yang Li, Alvin Lu et al. · Molecular Cell · 2016 · 175 citations · Full text

Death-inducing Signaling Complex, Signal Transduction, Protein Function +15