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A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein Translation

Donna N. Petersen, Julie A. Hawkins, Wanida Ruangsiriluk, Kimberly A. Stevens, Bruce A. Maguire, Thomas N. O’Connell, Benjamin N. Rocke, Markus Boehm, Roger B. Ruggeri, Tim Rolph,

Cell chemical biology · 2016 · 95 citations · 19 references

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19

Sequence Variations in <i>PCSK9,</i> Low LDL, and Protection against Coronary Heart Disease

Jonathan C. Cohen, Eric Boerwinkle, Thomas H. Mosley et al. · New England Journal of Medicine · 2006 · 3.2K citations · Full text

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Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

Marianne Abifadel, Mathilde Varret, Jean‐Pierre Rabès et al. · Nature Genetics · 2003 · 3K citations

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Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events

Jennifer G. Robinson, Michel Farnier, Michel Krempf et al. · New England Journal of Medicine · 2015 · 2.3K citations · Full text

, , +17

Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events

Marc S. Sabatine, Robert P. Giugliano, Stephen D. Wiviott et al. · New England Journal of Medicine · 2015 · 1.5K citations · Full text

, , +14

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

Weijia Kong, Jing Wei, Parveen Abidi et al. · Nature Medicine · 2004 · 1.4K citations

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