Concepedia

Post-translational Protein Processing

Post-Translational Protein Processing is a molecular biosynthetic mechanism that modifies newly synthesized polypeptides after ribosomal translation to achieve functional maturation, subcellular localization, or structural stability within the secretory pathway.

933

Publications

63K

Citations

3.7K

Authors

922

Institutions

Publications per year

2017–2026

81

Parents

Publications

933

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

Günter Blobel, B Dobberstein · The Journal of Cell Biology · 1975 · 3K citations · Full text

, , +12

Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components.

Günter Blobel, B Dobberstein · The Journal of Cell Biology · 1975 · 1.2K citations · Full text

, , +14

Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS

Peter E.A. Ash, Kevin F. Bieniek, Tania F. Gendron et al. · Neuron · 2013 · 1.1K citations · Full text

, , +7

Functional Regions of the Envelope Glycoprotein of Human Immunodeficiency Virus Type 1

Mark Kowalski, Joseph Potz, Ladan Basiripour et al. · Science · 1987 · 849 citations

, , +17

Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity.

David G. Perregaux, Christopher A. Gabel · Journal of Biological Chemistry · 1994 · 759 citations · Full text

, , +17

1–5 of 933

Authors

3.7K

  1. EM
    E. Michael Danielsen

    University of Copenhagen, Denmark

    8 publications · 259 citations

    8

    h-index

  2. GB
    Günter Blobel

    Rockefeller University, United States

    8 publications · 4.8K citations

    8

    h-index

  3. NG
    Nabil G. Seidah

    Montreal Clinical Research Institute, Canada

    7 publications · 1.3K citations

    7

    h-index

  4. CO
    Charles O. Brostrom

    Johnson University, United States

    6 publications · 557 citations

    6

    h-index

  5. CJ
    Chris J. Dickinson

    University of Michigan, United States

    6 publications · 171 citations

    6

    h-index

1–5 of 3.7K

Institutions

922

  1. National Institutes of Health

    Bethesda, United States

    22 h-index

    67 publications

    5K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    22 h-index

    75 publications

    11.1K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    97 publications

    5K citations

  4. Harvard University

    Cambridge, United States

    18 h-index

    64 publications

    17.4K citations

  5. Inserm

    Paris, France

    18 h-index

    90 publications

    2.8K citations

  6. Rockefeller University

    New York, United States

    15 h-index

    36 publications

    9.6K citations

  7. University of Copenhagen

    Copenhagen, Denmark

    15 h-index

    49 publications

    1.7K citations

  8. Washington University in St. Louis

    St Louis, United States

    14 h-index

    52 publications

    3.3K citations

1–8 of 922

Venues

  1. Journal of Biological Chemistry

    JBC · 230 publications · 17.4K citations

    74

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 37 publications · 4.4K citations

    33

    h-index

  3. Biochemical Journal

    BJ · 50 publications · 2.4K citations

    28

    h-index

  4. Journal of Virology

    JVI · 21 publications · 1.9K citations

    18

    h-index

  5. PubMed

    Repository · 23 publications · 699 citations

    18

    h-index

1–5