Peter E.A. Ash

Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS

Peter E.A. Ash, Kevin F. Bieniek, Tania F. Gendron et al. · Neuron · 2013 · 1.1K citations · Full text

Biochemistry, Unconventional Translation, Protein Folding +4

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

Chad A. Dickey, Adeela Kamal, Karen Lundgren et al. · Journal of Clinical Investigation · 2007 · 628 citations · Full text

Signal Recognition, Molecular Biology, Alzheimer's Disease +19

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

Yong‐Jie Zhang, Ya-Fei Xu, Casey Cook et al. · Proceedings of the National Academy of Sciences · 2009 · 606 citations · Full text

Apoptosis, Cell Death, Molecular Biology +18

Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS

Tania F. Gendron, Kevin F. Bieniek, Yong‐Jie Zhang et al. · Acta Neuropathologica · 2013 · 575 citations · Full text

Chromatin, Neurodegenerative Diseases, Rna Processing +14

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

Yong‐Jie Zhang, Karen Jansen‐West, Ya-Fei Xu et al. · Acta Neuropathologica · 2014 · 336 citations · Full text

Genetics, Aggregation-prone C9ftd/als Poly, Molecular Biology +17