Concepedia

The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome

Lawton K. Chung, Yong Hwan Park, Yueting Zheng, Igor E. Brodsky, Patrick Hearing, Daniel L. Kastner, Jae Jin Chae, James B. Bliska

Cell Host & Microbe · 2016 · 209 citations · 44 references

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44

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

, , +12

Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

Tariq Ghayur, Subhashis Banerjee, Margaret Hugunin et al. · Nature · 1997 · 1.2K citations

, , +11

Molecular Cloning of the Interleukin-1β Converting Enzyme

Douglas Pat Cerretti, Carl J. Kozlosky, Bruce Mosley et al. · Science · 1992 · 1.1K citations

, , +16

Critical Role for NALP3/CIAS1/Cryopyrin in Innate and Adaptive Immunity through Its Regulation of Caspase-1

Fayyaz S. Sutterwala, Yasunori Ogura, Marian Szczepanik et al. · Immunity · 2006 · 960 citations · Full text

, , +14

Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

Hao Xu, Jieling Yang, Wenqing Gao et al. · Nature · 2014 · 824 citations

, , +17