Margaret Hugunin

Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

Tariq Ghayur, Subhashis Banerjee, Margaret Hugunin et al. · Nature · 1997 · 1.2K citations

Cytokine, Transcriptional Regulation, Signal Transduction +10

Inhibition of ICE Family Proteases by Baculovirus Antiapoptotic Protein p35

Nancy J. Bump, Maria Hackett, Margaret Hugunin et al. · Science · 1995 · 641 citations

Biochemistry, Medicine, Natural Sciences +15

Crystal structure of the cysteine protease interleukin-1β-converting enzyme: A (p20/p10)2 homodimer

Nigel P.C. Walker, Robert V. Talanian, Kenneth D. Brady et al. · Cell · 1994 · 569 citations

Crystal Structure, Biochemistry, Natural Sciences +4

Proteolytic Activation of Protein Kinase C δ by an ICE/CED 3-like Protease Induces Characteristics of Apoptosis

Tariq Ghayur, Margaret Hugunin, Robert V. Talanian et al. · The Journal of Experimental Medicine · 1996 · 475 citations · Full text

Identification and Characterization of ICH-2, a Novel Member of the Interleukin-1β-converting Enzyme Family of Cysteine Proteases

Joanne Kamens, Michael Paskind, Margaret Hugunin et al. · Journal of Biological Chemistry · 1995 · 263 citations · Full text