Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

Cloning of a new cytokine that induces IFN-γ production by T cells

Haruki Okamura, Hiroko Tsutsui, Toshinori Komatsu et al. · Nature · 1995 · 2.6K citations

Immune Cell Development, Immunology, Immune Regulation +10

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

Inflammation, Cytokine, Granulocyte +6

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

Keisuke Kuida, Timothy S. Zheng, Songqing Na et al. · Nature · 1996 · 1.9K citations

Molecular Neuroscience, Apoptosis, Autophagy +12

Altered Cytokine Export and Apoptosis in Mice Deficient in Interleukin-1β Converting Enzyme

Keisuke Kuida, Judith A. Lippke, George Ku et al. · Science · 1995 · 1.6K citations

Interleukin-1β Converting Enzyme, Apoptosis, Immunology +17

Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock

Ping Li, Hamish Allen, Subhashis Banerjee et al. · Cell · 1995 · 1.4K citations · Full text

Inflammation, Cytokine, Immune Regulation +9