Haruki Okamura

Cloning of a new cytokine that induces IFN-γ production by T cells

Haruki Okamura, Hiroko Tsutsui, Toshinori Komatsu et al. · Nature · 1995 · 2.6K citations

Immune Cell Development, Immunology, Immune Regulation +10

Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme

Yong Gu, Keisuke Kuida, Hiroko Tsutsui et al. · Science · 1997 · 1.1K citations

IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production.

Tomohiro Yoshimoto, Kiyoshi Takeda, Takashi Tanaka et al. · PubMed · 1998 · 774 citations

T-regulatory Cell, Immunology, Immune Regulation +19

IL-12 Up-Regulates IL-18 Receptor Expression on T Cells, Th1 Cells, and B Cells: Synergism with IL-18 for IFN-γ Production

Tomohiro Yoshimoto, Kiyoshi Takeda, Takashi Tanaka et al. · The Journal of Immunology · 1998 · 666 citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +21

IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

Tomohiro Yoshimoto, Hiroko Tsutsui, Kouji Tominaga et al. · Proceedings of the National Academy of Sciences · 1999 · 435 citations · Full text