Crystal structure of the cysteine protease interleukin-1β-converting enzyme: A (p20/p10)2 homodimer

Improved methods for building protein models in electron density maps and the location of errors in these models

T. Alwyn Jones, Jin-yu Zou, Sandra W. Cowan et al. · Acta Crystallographica Section A Foundations of Crystallography · 1991 · 12.6K citations

Map Interpretation, Structural Bioinformatics, Biomolecular Structure Prediction +16

The protein data bank: A computer-based archival file for macromolecular structures

F. C. Bernstein, Thomas F. Koetzle, G. J. B. Williams et al. · Journal of Molecular Biology · 1977 · 8.6K citations

Structural Bioinformatics, Biomolecular Structure Prediction, Protein Folding +13

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

Annie Chang, Stanley N. Cohen · Journal of Bacteriology · 1978 · 4.3K citations · Full text

Amplifiable Multicopy Dna, Engineering, Dna Analysis +20

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

Axel T. Brünger · Nature · 1992 · 3.9K citations

Materials Science, Crystal Structure, Engineering +14

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

Inflammation, Cytokine, Granulocyte +6