Concepedia

Protease Domains

Protease Domain is a structural domain within a protein that belongs to the class of enzyme catalytic domains and is functionally specialized in the hydrolytic cleavage of peptide bonds through a defined active site architecture and catalytic mechanism.

765

Publications

57.4K

Citations

3.5K

Authors

852

Institutions

Publications per year

2017–2026

92

Variants

Protease Domain

Parents

Publications

765

On the size of the active site in proteases. I. Papain

Israël Schechter, Arieh Berger · Biochemical and Biophysical Research Communications · 1967 · 5.2K citations

, , +9

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

Rudolph E. Tanzi, Andrea I. McClatchey, Edward D. Lamperti et al. · Nature · 1988 · 1.1K citations

, , +14

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

Manuel A. Navia, Paula M.D. Fitzgerald, Brian M. McKeever et al. · Nature · 1989 · 893 citations

, , +16

A gated channel into the proteasome core particle.

M. Groll, Michael H. Glickman, Daniel Finley et al. · Nature Structural Biology · 2000 · 808 citations

, , +14

Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide

J.L Kim, Kurt Morgenstern, Chao Lin et al. · Cell · 1996 · 728 citations · Full text

, , +14

1–5 of 765

Authors

3.5K

  1. RH
    Robert Huber

    Max Planck Institute of Biochemistry, Germany

    11 publications · 1.5K citations

    11

    h-index

  2. AG
    Alla Gustchina

    Frederick National Laboratory for Cancer Research, United States

    8 publications · 576 citations

    8

    h-index

  3. BL
    Barbara Lipińska

    University of Gdańsk, Poland

    7 publications · 180 citations

    7

    h-index

  4. WB
    Wolfgang Baumeister

    Max Planck Institute of Biochemistry, Germany

    7 publications · 733 citations

    7

    h-index

  5. MN
    Michael N.G. James

    University of Alberta, Canada

    7 publications · 676 citations

    7

    h-index

1–5 of 3.5K

Institutions

852

  1. Max Planck Institute of Biochemistry

    Martinsried, Germany

    25 h-index

    99 publications

    12.9K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    20 h-index

    53 publications

    5.4K citations

  3. Scripps Research Institute

    San Diego, United States

    18 h-index

    61 publications

    4.6K citations

  4. National Institutes of Health

    Bethesda, United States

    15 h-index

    61 publications

    6.9K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    54 publications

    3.2K citations

  6. Max Planck Society

    Munich, Germany

    14 h-index

    44 publications

    7.5K citations

  7. University of California, San Francisco

    San Francisco, United States

    13 h-index

    51 publications

    3.9K citations

  8. Harvard University

    Cambridge, United States

    11 h-index

    32 publications

    10.5K citations

1–8 of 852

Venues

  1. Journal of Biological Chemistry

    JBC · 110 publications · 8.2K citations

    56

    h-index

  2. Journal of Molecular Biology

    JMB · 51 publications · 3.5K citations

    34

    h-index

  3. Biochemistry

    40 publications · 2K citations

    27

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 22 publications · 3.5K citations

    22

    h-index

  5. FEBS Letters

    22 publications · 1.3K citations

    18

    h-index

1–5