Manuel A. Navia

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Publications

Citations

6.9K

H-Index

Active since

1972

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Vertex Pharmaceuticals (United States)

National Institutes of Health

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Manuel A. Navia is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in life sciences, structural biology, and protein structure.

Publications per year

1972–2023

Publications

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

Manuel A. Navia, Paula M.D. Fitzgerald, Brian M. McKeever et al. · Nature · 1989 · 893 citations

Life Sciences, Biochemistry, Molecular Biology +16

Structure and mechanism of interleukin-lβ converting enzyme

Keith P. Wilson, Jo-Anne F. Black, John A. Thomson et al. · Nature · 1994 · 843 citations

Life Sciences, Biochemistry, Molecular Biology +11

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

James P Griffith, Joseph L. Kim, Eunice E Kim et al. · Cell · 1995 · 838 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1

Andrew D. Napper, Jeffrey Hixon, Thomas McDonagh et al. · Journal of Medicinal Chemistry · 2005 · 525 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Crystal structure of HIV-1 protease in complex with VX-478, a potent and orally bioavailable inhibitor of the enzyme

E. E. Kim, Christopher Baker, M.D. Dwyer et al. · Journal of the American Chemical Society · 1995 · 391 citations

Life Sciences, Biochemistry, Medicinal Chemistry +14

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