Thomas McDonagh

Substrate-specific Activation of Sirtuins by Resveratrol

Matt Kaeberlein, Thomas McDonagh, Birgit Heltweg et al. · Journal of Biological Chemistry · 2005 · 735 citations · Full text

Yeast Sir2, Reductive Stress, Biosynthesis +13

Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells

Laura Bordone, Maria Carla Motta, Frédéric Picard et al. · PLoS Biology · 2005 · 702 citations · Full text

Insulin Signaling, Metabolic Syndrome, Signaling Pathway +16

Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1

Andrew D. Napper, Jeffrey Hixon, Thomas McDonagh et al. · Journal of Medicinal Chemistry · 2005 · 520 citations · Full text

Medicinal Chemistry, Herein Inhibit Sirt1, Bioorganic Chemistry +15

Inhibition of SIRT1 Catalytic Activity Increases p53 Acetylation but Does Not Alter Cell Survival following DNA Damage

Jonathan M. Solomon, Rao Pasupuleti, Lei Xu et al. · Molecular and Cellular Biology · 2005 · 483 citations · Full text

Dna Damage, Apoptosis, Cell Death +16

Crystal Structure of the Wild-type von Willebrand Factor A1-Glycoprotein Ibα Complex Reveals Conformation Differences with a Complex Bearing von Willebrand Disease Mutations

John J. Dumas, R. Anand Kumar, Thomas McDonagh et al. · Journal of Biological Chemistry · 2004 · 199 citations · Full text