John A. Thomson

Structure and mechanism of interleukin-lβ converting enzyme

Keith P. Wilson, Jo-Anne F. Black, John A. Thomson et al. · Nature · 1994 · 840 citations

Protein Expression, Cellular Enzymology, Biochemistry +5

Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide

J.L Kim, Kurt Morgenstern, Chao Lin et al. · Cell · 1996 · 723 citations · Full text

Crystal Structure, Biochemistry, Natural Sciences +5

Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease

Robert B. Perni, Susan J. Almquist, Randal A. Byrn et al. · Antimicrobial Agents and Chemotherapy · 2006 · 382 citations · Full text

Binary liquid phase separation and critical phenomena in a protein/water solution.

John A. Thomson, Peter Schurtenberger, George M. Thurston et al. · Proceedings of the National Academy of Sciences · 1987 · 276 citations · Full text

Engineering, Molecular Biology, Coexistence Curve +18

A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro

Chao Lin, John A. Thomson, Charles M. Rice · Journal of Virology · 1995 · 217 citations · Full text

Virus Structure, Catalytic Domain, Central Region +13