Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

Non-canonical inflammasome activation targets caspase-11

Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi et al. · Nature · 2011 · 2.5K citations

Life Sciences, Cell Biology, Immunology +12

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

Tomáš Čermák, Erin Doyle, Michelle Christian et al. · Nucleic Acids Research · 2011 · 2.1K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +10

A candidate gene for familial Mediterranean fever

Alain Bernot, Christian Clépet, Corinne Da Silva et al. · Nature Genetics · 1997 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +7

Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever

The International FMF Consortium · Cell · 1997 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

Yue Zhao, Jieling Yang, Jianjin Shi et al. · Nature · 2011 · 1.3K citations

Life Sciences, Immunology, Microbiology +16