Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

Non-canonical inflammasome activation targets caspase-11

Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi et al. · Nature · 2011 · 2.4K citations

Inflammation, Anti-inflammatory, Immunology +6

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

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Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever

The International FMF Consortium · Cell · 1997 · 1.5K citations · Full text

Mendelian Disorder, Reverse Genetics, Genetic Disorder +9

A candidate gene for familial Mediterranean fever

Nature Genetics · 1997 · 1.5K citations

Genetics, Pathogenesis, Genetic Epidemiology +4

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

Yue Zhao, Jieling Yang, Jianjin Shi et al. · Nature · 2011 · 1.2K citations

Bacterial Flagellin, Protein Secretion, Nlrc4 Inflammasome Receptors +9