Concepedia

Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site

Jack Exell, Mark J. Thompson, L. David Finger, Steven J. Shaw, J.E. Debreczeni, Thomas A. Ward, Claire McWhirter, Catrine L. B. Siöberg, Daniel Martinez Molina, W. Mark Abbott,

Nature Chemical Biology · 2016 · 77 citations · 47 references

DOIFull text

Open access

Concepts

References

47

Features and development of <i>Coot</i>

Paul Emsley, Bernhard Lohkamp, W. G. Scott et al. · Acta Crystallographica Section D Biological Crystallography · 2010 · 29.6K citations · Full text

, , +16

The CCP4 suite: programs for protein crystallography

Number Collaborative Computational Project · Acta Crystallographica Section D Biological Crystallography · 1994 · 17.3K citations

, , +15

Protein production by auto-induction in high-density shaking cultures

F. William Studier · Protein Expression and Purification · 2005 · 6.1K citations

, , +12

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

F. Niesen, H. Berglund, Masoud Vedadi · Nature Protocols · 2007 · 2.4K citations

, , +14

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

Daniel Martinez Molina, Rozbeh Jafari, Marina Ignatushchenko et al. · Science · 2013 · 2.2K citations

, , +17