Jack Exell

Real-time 3D single molecule tracking

Shangguo Hou, Jack Exell, Kevin Welsher · Nature Communications · 2020 · 98 citations · Full text

Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site

Jack Exell, Mark J. Thompson, L. David Finger et al. · Nature Chemical Biology · 2016 · 75 citations · Full text

Molecular Pharmacology, Substrate Entry, Drug Target +10

Capturing the start point of the virus–cell interaction with high-speed 3D single-virus tracking

Courtney Johnson, Jack Exell, Yuxin Lin et al. · Nature Methods · 2022 · 48 citations · Full text

Viral Replication, Single-virus Tracking, Viral Polymerase Structure +9

Flap endonucleases pass 5′-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5′-ends

Nikesh Patel, John M. Atack, L. David Finger et al. · Nucleic Acids Research · 2012 · 44 citations · Full text

Observation of unpaired substrate DNA in the flap endonuclease-1 active site

L. David Finger, Nikesh Patel, Amanda Beddows et al. · Nucleic Acids Research · 2013 · 32 citations · Full text