Nature Biotechnology · 2016 · 213 citations · 45 references
Life SciencesGeneticsMolecular BiologyGenetic EngineeringGenome EditingSynthetic BiologyAllosteric Modulator DesignAllosteric Regulation EngineeringCrispr-based EngineeringCrispr-cas SystemsTarget Site SelectionCrispr-based Genome EngineeringCrispr-cas9 Genome Editing
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Initial sequencing and analysis of the human genome
Eric S. Lander, Lauren Linton, Bruce W. Birren et al. · Nature · 2001 · 24.6K citations · Full text
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
Differential expression analysis for sequence count data
Simon Anders, Wolfgang Huber · Genome biology · 2010 · 16.4K citations · Full text
Enzymatic assembly of DNA molecules up to several hundred kilobases
Daniel G. Gibson, Lei Young, Ray-Yuan Chuang et al. · Nature Methods · 2009 · 10.9K citations
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
Lei S. Qi, Matthew H. Larson, Luke A. Gilbert et al. · Cell · 2013 · 5.2K citations · Full text