Concepedia

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model

Vaishali Kakkar, Cecilia Månsson, Eduardo Preusser de Mattos, Steven Bergink, Marianne van der Zwaag, Maria A.W.H. van Waarde, Niels Kloosterhuis, Ronald Melki, Remco T. P. van Cruchten, Salam Al‐Karadaghi,

Molecular Cell · 2016 · 204 citations · 45 references

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References

45

Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis

Chengkai Dai, Luke Whitesell, Arlin B. Rogers et al. · Cell · 2007 · 839 citations · Full text

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Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70

John M. Warrick, Ho Yin Edwin Chan, Gladys L. Gray-Board et al. · Nature Genetics · 1999 · 833 citations

, , +14

Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin

Rona K. Graham, Yu Deng, Elizabeth Slow et al. · Cell · 2006 · 649 citations · Full text

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Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

Shermali Gunawardena, Lu‐Shiun Her, Richard G. Brusch et al. · Neuron · 2003 · 642 citations · Full text

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Aberrant splicing of <i>HTT</i> generates the pathogenic exon 1 protein in Huntington disease

Kirupa Sathasivam, Andreas Neueder, Theresa A. Gipson et al. · Proceedings of the National Academy of Sciences · 2013 · 545 citations · Full text

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