Remco T. P. van Cruchten

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model

Vaishali Kakkar, Cecilia Månsson, Eduardo Preusser de Mattos et al. · Molecular Cell · 2016 · 197 citations · Full text

Molecular Regulation, Natural Sciences, Dna Replication +9

Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation

Cecilia Månsson, Remco T. P. van Cruchten, Ulrich Weininger et al. · Biochemistry · 2018 · 59 citations

Protein Assembly, Molecular Biology, Neurochemical Biomarkers +19

(CTG)n repeat-mediated dysregulation of MBNL1 and MBNL2 expression during myogenesis in DM1 occurs already at the myoblast stage

Laurène M. André, Remco T. P. van Cruchten, Marieke Willemse et al. · PLoS ONE · 2019 · 20 citations · Full text

Genetics, Myoblast Stage, Mbnl3 Rnas +16

Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG)n Repeat

Laurène M. André, Remco T. P. van Cruchten, Marieke Willemse et al. · International Journal of Molecular Sciences · 2019 · 20 citations · Full text

Expanded CUG repeats in <i>DMPK</i> transcripts adopt diverse hairpin conformations without influencing the structure of the flanking sequences

Remco T. P. van Cruchten, Bé Wieringa, Derick G. Wansink · RNA · 2019 · 19 citations · Full text